Authors

Ponto LL. Ponto JA.

Institution

Department of Radiology, University of Iowa, Iowa City.

Title

Uses and limitations of positron emission tomography in clinical pharmacokinetics/dynamics (Part I). [Review] [0 refs]

Source

Clinical Pharmacokinetics. 22(3):211-22, 1992 Mar.

Abstract

Positron emission tomography (PET) involves imaging the biodistribution and tissue localisation of small amounts of radiolabelled biomolecules or drugs. In Part I of this article, the applications of pharmacokinetics in PET are discussed in order to derive quantitative measures of physiological function. Part II will examine the use of PET imaging as a tool to study the pharmacokinetics and pharmacodynamics of specific drugs. [References: 0]