Creutzfeldt - Jakob Disease

Patient History

71 year old female, possible Cruetzfeldt-Jakob Disease.

Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. Typically, onset of symptoms occurs at about age 60. There is currently no single diagnostic test for CJD. The first concern is to rule out treatable forms of dementia such as encephalitis or chronic meningitis. The only way to confirm a diagnosis of CJD is by brain biopsy or autopsy.

Study Findings

Abnormal ¹⁸F FDG P.E.T. brain scan. Relative decreased metabolism in the right anterior and inferior medial temporal lobe, right posterior parietal lobe and in the right parietal temporal lobe region. Mild decrease metabolism in the right basal ganglia.

Reference

Goldman, S., Liaed, A., Flament, Durand, Luxen, Al, Bidaut, L.M., Stanus, E., Hildebrand, J., Przedborski, S., "Positron emission tomography and histopathology in Creutzfeldt-Jakob disease" Neurology, Vol. 43, September 1993, pp 1828-30.

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